"The fictional town which gives its name to the series is home to a 77-year-old, plump and childish little man with an oversized hat -- a pope who likes to play hide and seek, doesn't wash for months, wants to drink Coca Cola but isn't allowed to and enjoys bouncing through hallways on a cross-shaped pogo stick. Popetown's true rulers are three corrupt cardinals who dwell in a wellness spa hidden behind a bookshelf, and who spend their days ruminating over how they can become the richest men in the world. Other inhabitants of the town include a young priest, a dim-witted nun and a cardinal with a sexual preference for exotic animals."
I know that Islamophobes will be pointing out to how "civilized" Catholic protests to the series have been, compared to the violent Muslim protests of the Danish cartoons.
But Catholics in Germany and Europe generally are not a persecuted minority. The Pope is not an underdog. European Catholics don't live in countries invaded by other countries that believe they are, on the whole, brutes that need to be exterminated. Only if you have these similar conditions (among others), you can compare the reaction.